PEGylated Streptokinase

pegylated streptokinase

Question- ‘PEGylated streptokinase’ (a new biological entity) helpful in the treatment of –
(a)Ischemic stroke
(b)Cancer
(c)Diabetes
(d)None of the above
Answer- a
Related facts-

  • A new Clot buster, PEGylated Streptokinase – a unique Biological Entity has recently developed by inventors of CSIR-Institute of Microbial Technology (CSIRIMTECH), Girish Sahni, DG, CSIR and Secretary, and his team of inventors at CSIR-Institute of Microbial Technology (CSIR-IMTECH), Chandigarh. This new invention is all set to revolutionize the treatment of ischemic strokes.

About PEGylated streptokinase-

  • It a novel recombinant protein that has been proved very helpful in the treatment of ischemic stroke as it dissolves blood clots.
  • It is CSIR’s new patented clot buster biological entity.

About Ischemic stroke-

  • Brain depends on its arteries to bring fresh blood from the heart and lungs which carries oxygen and nutrients to it and takes away carbon dioxide and cellular waste, whenever these arteries gets blocked the brain stops working and leads to a massive stroke.
  • Ischemic stroke is of two types :-

(a) Thrombotic stroke occurs when diseased or damaged cerebral arteries become blocked by the formation of a blood clot within the brain.

(b)  Embolic stroke is also caused by a clot within an artery, but in this case the clot (or emboli) forms somewhere other than in the brain itself.  Often from the heart, these emboli will travel in the bloodstream until they become lodged and cannot travel any farther.

Facts-

  • According to the American Stroke Association (ASA), brain strokes are the second leading cause of death in the world with a staggering 15 million people effected causing 11 million people either die or become permanently disabled. Surprisingly, the prevalence of stroke is much higher in India than the West and about 87% of all strokes are ischemic strokes.

References-
http://pib.nic.in/newsite/PrintRelease.aspx?relid=181847
http://www.strokecenter.org/patients/about-stroke/ischemic-stroke/