{"id":115919,"date":"2021-06-21T14:03:05","date_gmt":"2021-06-21T14:03:05","guid":{"rendered":"https:\/\/www.edristi.in\/?p=115919"},"modified":"2021-06-21T14:03:07","modified_gmt":"2021-06-21T14:03:07","slug":"monoclonal-antibodies-covid","status":"publish","type":"post","link":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/monoclonal-antibodies-covid\/","title":{"rendered":"Monoclonal antibodies &amp; Covid"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Question- Consider the following statements about Monoclonal antibodies-<br>(1) Monoclonal antibodies are artificial antibodies that mimic the activity of our immune systems.<br>(2) They are produced through a process that involves extracting specific antibodies from human blood and then cloning them.<br>Select the correct answer using the code given below-<\/strong><br>(a) Only 1<br>(b) Only 2<br>(c) Both 1 and 2<br>(d) Neither 1 nor 2<br><strong>Ans. (c)<br>Related Facts-<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>An experimental monoclonal antibody cocktail, REGEN-COV2, has been found to be a life-saving treatment for some of the most severely affected Covid-19 patients, results of a clinical trial in the UK have shown.<\/li><li>To fight a viral infection, our bodies create proteins known as antibodies. Monoclonal antibodies are artificial antibodies that mimic the activity of our immune systems.<\/li><li>They are produced through a process that involves extracting specific antibodies from human blood and then cloning them.<\/li><li>These monoclonal antibodies are designed to target a virus or a specific part of one- for instance, REGEN-COV2 is a cocktail of two monoclonal antibodies developed to target the SARS-CoV-2 spike protein.<\/li><li>The monoclonal antibodies bind to specific parts of the spike protein, blocking its ability to infect healthy cells.<\/li><li>Besides Covid-19, monoclonal antibodies have been used in the treatment of cancers as well as Ebola and HIV.<\/li><li>The University of Oxford said last week that its RECOVERY trials found that for hospitalised patients with severe Covid-19 \u201cwho have not mounted a natural antibody response of their own\u201d, Regeneron\u2019s monoclonal antibody cocktail reduces the risk of death by a fifth compared to those who had received standard care. \u201cThus, for every 100 such patients treated with the antibody combination, there would be six fewer deaths.<\/li><li>REGEN-COV2 is available in India through a tie-up between Swiss drug giant Roche and Indian company Cipla.<\/li><li>The therapy, a combination of monoclonal antibodies casirivimab and imdevimab, had received the Central Drugs Standard Control Organisation\u2019s restricted emergency use permission in May.<\/li><\/ul>\n\n\n\n<p class=\"has-text-align-right wp-block-paragraph\"><strong>By- Yogesh Pratap Singh<\/strong><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Reference- <\/strong><a href=\"https:\/\/indianexpress.com\/article\/explained\/explained-monoclonal-antibodies-covid-7368039\/.\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/indianexpress.com\/article\/explained\/explained-monoclonal-antibodies-covid-7368039\/.<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Question- Consider the following statements about Monoclonal antibodies-(1) Monoclonal antibodies are artificial antibodies that mimic the activity of our immune systems.(2) They are produced through a process that involves extracting specific antibodies from human blood and then cloning them.Select the correct answer using the code given below-(a) Only 1(b) Only 2(c) Both 1 and 2(d) [&hellip;]<\/p>\n","protected":false},"author":9,"featured_media":115920,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1123],"tags":[3067],"class_list":["post-115919","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-snes","tag-scientific"],"_links":{"self":[{"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/posts\/115919","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/comments?post=115919"}],"version-history":[{"count":1,"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/posts\/115919\/revisions"}],"predecessor-version":[{"id":115921,"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/posts\/115919\/revisions\/115921"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/media\/115920"}],"wp:attachment":[{"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/media?parent=115919"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/categories?post=115919"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.edristi.in\/hi\/%e0%a4%b9%e0%a5%8b%e0%a4%ae\/wp-json\/wp\/v2\/tags?post=115919"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}